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AASs exert their effects by activating androgen receptor (AR) signaling. Several portions of the human body are involved as a result of presence of ARs in many tissues [12]. At standard physiologic amounts of testosterone androgen receptors are saturated plus the AASs effects could be a consequence of other mechanisms rather than androgen receptors
Inside of these cells, AAS can biotransform into various metabolites or bind to their cognate receptor: the androgen receptor. AAS and their metabolites could potentially cause Negative effects which include acne vulgaris, hypertension, hepatotoxicity, dyslipidemia, testosterone deficiency, erectile dysfunction, gynecomastia, and cardiomyopathy. Wh
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